26/F G4P1L1A2 ?ITP

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Case:

26year female came to casualty as she was referred from outside hospital in view of thrombocytopenia in pregnancy 

No previous comorbidities

HOPI:

1st pregnancy P1L1 ,5yrs male child ,LSCS in view of PROM


2nd pregnancy in view of bleeding PV visited hospital at 1 and half month Gestation--threatened abortion


3rd pregnancy- Spontaneous abortion,went to hospital for regular check up and was told to have absent Fetal heart sounds and was given Medication for MTP

After 1year patient was admitted in our hospital with fever ,low back ache ,headache and was told to have low platelets 34k,was managed with IV fluids ,improved to 1.05L at discharge and 1.5L later on follow up one week later

She did not have any bleeding manifestations at that time

After 1 year (this pregnancy) spontaneously conceived ,6months of amennorhea now

No use of any contraception in between the pregnancies

C/o bleeding from gums from 2days before admission while brushing teeth,petechial rash on right hand since 1day

She went on a regular antenatal check up at outside hospital and was found to have platelets 20k and was referred to our hospital.

No c/o hematuria,blood in stools,hemetemesis,hemoptysis

Ist Trimester -h/o vomitings (subsided later),no h/o fever with rash,no h/o radiation exposure,white discharge pv,spotting pv,early obs scan was normal

2nd trimester -quickenint felt at 5th month ,TIFFA normal done at 17 weeks

Lmp 6/4/2022

Edd 13/1/2023

Sedd 7/1/2023(9weeks,3days)

POG 25weeks +3days

Past history

No h/o DM ,HTN,CAD,CVA, Epilepsy, previous bleeding disorders

Personal history:

Diet- mixed

Appetite- normal 

Sleep- Adequate

Bowl and bladder movements: regular

Menstrual history:

Menarche - 13years

3-5 Days/30 cycle

LMP- 6/04/2022

OBSTETRIC HISTORY :

Age at marriage- 18 Years

Age at first child birth- 20 Years

Gravida- 4

Para- 1

No. Of living children- 1

No. Of abortions- 2 at 6 weeks

GENERAL EXAMINATION:

After taking consent, the pateint was examined in a well lit room.

The patient is conscious, coherent, cooperative and we'll oriented to time, place and person.

She is thin built and moderately nourished.

No pallor, icterus, cyanosis, clubbing, lymphadenopathy, Edema, dehydration.

Temperature - Afebrile

Pulse - 80bpm 

Respiratory rate - 16cpm, regular

Blood pressure - 100/60 mmHg 

SpO2 - 99% at room air.

Hess test negative



Petechial rash

Systemic examination 

CVS- S1 S2+

RS- BAE+

CNS- INTACT

Investigations

Day 1










Day 2




Day 3



PROVISIONAL DIAGNOSIS:

A 26 YEAR FEMALE, G4P1L1A2 with 25 weeks 3 days GA with previous LSCS with 

?Gestational Thrombocytopenia

 ?ITP,

?APLA 


TREATMENT:

Day 1

1. 1 SDP TRANSFUSION

2. Daily Fetal heart, Fetal movements count monitoring 

3. T. FERROUS ASCORBATE 100MG PO/BD

4. T. CALCIUM 1000MG PO/BD

5. T. ULTA MW 500MG PO/OD

6. T. MVT PO/OD

7. GRBS MONITORING 

Day 2

1.T. FERROUS ASCORBATE 100MG PO/BD

2.T. CALCIUM 1000MG PO/BD

3.T. ULTA MW 500MG PO/OD

4.T. MVT PO/OD




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